The level of cell apoptosis in pulmonary tissues of 7d tail - suspended rats during simulated weightlessness increased significantly ( p < 0 . 01 ) , but that of 21 d had not a prominent change ( p > 0 . 05 ) . conclusion 1 . simulated weightlessness in tail - suspended rats has certain effects on lung function . fevo . 3 % , peak expiratory flow ( pef ) and maximal voluntary ventilation ( mvv ) tend to decrease , especially fevo . 3 % in 7d and mvv in 21d decrease significantly 3 、大鼠肺組織普遍存在凋亡細胞, 7d尾懸吊模擬失重大鼠肺組織細胞凋亡水平明顯高于對照組,且具有統(tǒng)計學意義( p 0 . 01 ,但21d尾懸吊軍醫(yī)進修學院碩士學位論文尾懸吊模擬失重對大鼠肺臟的影響模擬失重大鼠肺組織細胞凋亡水平與對照組相比無顯著性差別o 0刀5卜結論1 、尾懸吊模擬失重對大鼠肺功能有一定影響。